It proves to be pretty difficult to remove nail polish when your bottle of remover gives you its last drop. What to do when you’re in a pinch like this? Create your own nail polish remover alternatives at home! Vinegar, rubbing alcohol, or even a lemon slice are acidic enough to loosen the polish on your nails. Because it takes a little longer to soften the nail polish, for best results, soak nails in warm soapy water for five minutes then continue on to soak a cotton ball with either of the three acidic solutions above and put off the trip to the drug store for another time!